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Journal of Applied Physics / Volume 109 / Issue 7 / PROCEEDINGS OF THE 55TH ANNUAL CONFERENCE ON MAGNETISM AND MAGNETIC MATERIALS / Magnetic Sensors, MEMS, Power, High-Frequency Devices

J. Appl. Phys. 109, 07E532 (2011); http://dx.doi.org/10.1063/1.3564951 (3 pages)

High-sensitivity detector for molecular sensing using magnetic particles

D. Le Roy1,2, W. Yang1,3, X. Yin1,2, R. Y. Lai1,3, S.-H. Liou1,2, and D. J. Sellmyer1,2

1Nebraska Center for Materials and Nanoscience, Lincoln, Nebraska 68588, USA
2Department of Physics and Astronomy, University of Nebraska, Lincoln, Nebraska 68588, USA
3Department of Chemistry, University of Nebraska, Lincoln, Nebraska 68588, USA

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(Received 23 September 2010; accepted 15 December 2010; published online 6 April 2011)

A scheme for molecular sensing using magnetic tracer particles and a microcantilever torsional magnetometer is investigated. The present report deals with the example of explosive 2,4,6-trinitrotoluene (TNT) detection. The sensors consist of silicon microcantilevers functionalized with TNT aptamers that are weakly bonded to magnetic particles via TNT-analog molecules. When exposed to TNT, the magnetic signal, initially maximum, is expected to undergo a steplike decrease as the TNT molecules replace the magnetic particles on the TNT receptors. We demonstrate the feasibility of this detection technique in terms of chemical reactions and our magnetometer sensitivity that reaches the range of 10−11 emu at room temperature with commercial atomic force microcopy cantilevers.

© 2011 American Institute of Physics

Article Outline

  1. INTRODUCTION
  2. EXPERIMENTAL DETAILS
  3. RESULTS AND DISCUSSION

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KEYWORDS and PACS

Keywords

atomic force microscopy, cantilevers, chemical reactions, chemical sensors, explosives, magnetic particles, magnetic sensors, magnetometers, microsensors, silicon

PACS

  • 07.55.-w

    Magnetic instruments and components

  • 07.07.Df

    Sensors (chemical, optical, electrical, movement, gas, etc.); remote sensing

  • 07.10.Cm

    Micromechanical devices and systems

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.3564951

PUBLICATION DATA

ISSN

0021-8979 (print)  
1089-7550 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

For access to fully linked references, you need to log in.
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