NASA’s mission requirements for spaceborne laser diode arrays lead to a set of tests peculiar to space flight. The goal of these tests is to determine if vibration, radiation, or vacuum will impair the operation or lifetime of nominally 100 W quasicontinuous wave 808 nm laser diode arrays. To simulate the stresses expected during a mission, terrestrial tests involve mechanical vibration, simulating the acceleration of launch, exposure to the equivalent doses of ionizing radiation, and operation in a vacuum. Three sets of devices were tested: one set with random vibration up to 20 g root-mean-square (grms) applied along three axes, a second set of devices was irradiated with γ radiation (1.17 and 1.33 MeV) at 744 rad(Si)∕min up to 200 krad(Si), and the third set was exposed to a flux of 5×1011 or 1012 p/cm2 of 200 MeV protons up to 60 krad total dose. Only the proton irradiated devices showed any effect attributable to the test: a slight rise in lasing threshold, which recovered over time with self-annealing. A selection of the devices were then operated in vacuum for a further 1400 h accumulating 500×106 pulses without any signs of degradation. Similar results were obtained in a parallel test, conducted in air, accumulating over 109 pulses on a selection of the remaining devices.